Guillain-Barré syndrome is a rare condition that causes the immune system to attack the nerves outside of the brain and spinal cord. It is characterized by numbness, tingling, weakness, or paralysis in the legs, arms, breathing muscles, and face. It can affect all ages.

Nervous System
CNS and PNS
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The exact cause of Guillain-Barré syndrome is unknown. However, in about 70% of patients, a recent infection or surgery is a trigger to an autoimmune response. This autoimmune response attacks the peripheral nerves, leading to weakness and a loss of sensation.